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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GYS1
All Species:
20.61
Human Site:
S718
Identified Species:
32.38
UniProt:
P13807
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13807
NP_002094.2
737
83786
S718
V
D
T
A
T
S
S
S
L
S
T
P
S
E
P
Chimpanzee
Pan troglodytes
XP_520790
703
80912
P684
D
R
L
N
I
K
S
P
F
S
L
S
H
V
P
Rhesus Macaque
Macaca mulatta
Q8MJ26
737
83768
S718
V
D
T
A
T
S
S
S
L
S
T
P
S
E
P
Dog
Lupus familis
XP_534869
703
80957
P684
D
R
L
N
I
K
S
P
F
S
L
G
R
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E4
738
83908
S719
V
D
T
G
P
S
S
S
L
S
T
P
T
E
P
Rat
Rattus norvegicus
A2RRU1
738
84053
S719
V
D
T
G
P
S
S
S
L
S
T
P
T
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505471
733
83148
S714
V
D
T
A
P
S
S
S
A
S
S
L
S
E
P
Chicken
Gallus gallus
XP_416432
704
81032
I682
A
E
R
D
R
Q
N
I
K
S
P
F
S
L
G
Frog
Xenopus laevis
NP_001084863
702
80811
T683
D
R
Q
N
I
K
S
T
F
S
F
G
P
V
S
Zebra Danio
Brachydanio rerio
NP_957474
700
80455
P682
D
R
V
N
I
R
Q
P
Y
N
L
P
N
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VFC8
709
81735
T683
P
T
S
S
R
H
T
T
P
A
P
S
V
H
G
Honey Bee
Apis mellifera
XP_624707
692
79590
E674
S
V
H
G
S
D
E
E
D
E
V
D
D
E
K
Nematode Worm
Caenorhab. elegans
Q9U2D9
672
76441
S654
D
N
E
G
K
V
P
S
A
A
T
S
R
R
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23337
708
80492
G690
Y
F
N
L
S
T
N
G
A
I
D
N
D
D
D
Red Bread Mold
Neurospora crassa
O93869
706
80888
T688
P
L
T
L
K
Q
R
T
G
P
G
S
P
L
D
Conservation
Percent
Protein Identity:
100
68.6
99
69.3
N.A.
96.6
96.6
N.A.
90
71
69.3
78.1
N.A.
55
56.4
49.6
N.A.
Protein Similarity:
100
81.8
99.5
82.5
N.A.
98.5
98.5
N.A.
95.2
84.1
82.5
86.5
N.A.
71
70.1
65.8
N.A.
P-Site Identity:
100
20
100
20
N.A.
80
80
N.A.
73.3
13.3
13.3
6.6
N.A.
0
6.6
20
N.A.
P-Site Similarity:
100
20
100
20
N.A.
86.6
86.6
N.A.
80
26.6
20
20
N.A.
33.3
13.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50
51.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
67.1
67
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
20
0
0
0
0
20
14
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
34
0
7
0
7
0
0
7
0
7
7
14
7
14
% D
% Glu:
0
7
7
0
0
0
7
7
0
7
0
0
0
40
0
% E
% Phe:
0
7
0
0
0
0
0
0
20
0
7
7
0
0
0
% F
% Gly:
0
0
0
27
0
0
0
7
7
0
7
14
0
0
14
% G
% His:
0
0
7
0
0
7
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
0
0
27
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
14
20
0
0
7
0
0
0
0
0
7
% K
% Leu:
0
7
14
14
0
0
0
0
27
0
20
7
0
14
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
27
0
0
14
0
0
7
0
7
7
0
7
% N
% Pro:
14
0
0
0
20
0
7
20
7
7
14
34
14
0
54
% P
% Gln:
0
0
7
0
0
14
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
27
7
0
14
7
7
0
0
0
0
0
14
14
0
% R
% Ser:
7
0
7
7
14
34
54
40
0
60
7
27
27
0
7
% S
% Thr:
0
7
40
0
14
7
7
20
0
0
34
0
14
0
0
% T
% Val:
34
7
7
0
0
7
0
0
0
0
7
0
7
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _